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Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (title previously utilized: bishydroxycoumarin) and causes a lessen in anticoagulant action as calculated because of the prothrombin time. Barbiturates can induce hepatic microsomal enzymes leading to elevated metabolism and lowered anticoagulant reaction of oral anticoagulants (e.

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Drug interactions: Most reports of clinically sizeable website drug interactions transpiring Using the barbiturates have associated phenobarbital.

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